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At the onset of Ulcerative cholitis, I was on high doses of Prednisone with the Asacol. My husband took prednisone for close to the same reason you are and if you can do with out please do. Prednisone may also mask some of the signs of an infection, making it difficult for your doctor to diagnose the actual problem. Prednisone can be effective, but it does have nasty side effects for lots of people. We can have an unpleasant experience if we use prednisone a long time and then stop abruptly.
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